Belgium defeated Wales 4-2 in the World Cup preliminaries. De Bruyne scored twice from the penalty spot and Trossard scored.

In the European preliminaries of the World Cup on October 14, Belgium defeated Wales 4-2 away from home.

In the first half of this campaign, Rodon took the lead for Wales, De Bruyne shot to equalize the score, Doku assisted Meunier to score, and Belgium went ahead 2-1. In the second half, De Bruyne scored another goal from the penalty spot, scoring twice, Broadhead regained one for Wales, and Trossard sealed the victory for Belgium. In the end, Belgium defeated Wales 4-2 away from home.

After this game, Belgium ranked first in Group J with 4 wins, 2 draws and 14 points, while Wales ranked third with 10 points and 3 wins, 1 draw and 2 losses.